LIASHyC is governed by two general directors and two scientific directors. At the moment these are:
- Prof. John Molson, University of Laval (general director)
- Dr. James Irving, University of Lausanne (general director)
- Prof. Erwan Gloaguen, Intitut National de la Recherche Scientifique (scientific director)
- Prof. Philip Brunner, University of Neuchâtel (scientific director)